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Abstract: In the past few years concerns over the possibility of terrorist actions against domestic and military water supplies has become paramount. Antibodies, peptides, and enzymes have been used as molecular recognition elements in chemical sensors; however, such devices often have storage and operational stability issues that limits their success. Molecularly imprinted polymers (MIPs), have been successfully demonstrated an alternative in pesticide applications [A.L. Jenkins, R. Yin, J.J. Jensen, Analyst 126 (2001) 798-802]. The MIP materials possess selective molecular recognition properties that are complementary to the analyte in the shape and positioning of functional groups. These polymers have high selectivity and affinity constants while maintaining excellent thermal and mechanical stability. In this study, direct imprinting of chemical agents EA2192, VX, sarin, and soman (the "G" agents), was performed and the limits of detection calculated. The ability of these sensors to work in various water matrices including tap, deionized and reverse osmosis water with residual chlorine was also evaluated. Typical detection limits for these MIP sensors are approximately 50 ppt with wide linear dynamic ranges (ppt-ppm). Sensor response time is approximately 15 min
Template and target information: chemical warfare agents, EA2192, VX, sarin, soman, "G" agents
Author keywords: Molecularly imprinted polymers, chemical agents, luminescence, detection