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Reference type: Journal
Authors: Nakagawa H, Muraki M, Miura Y, Kinoshita M
Article Title: Spacer effect in the template polycondensation of nucleotide analogs with diamines.
Publication date: 1982
Journal: Makromolekulare Chemie-Macromolecular Chemistry And Physics
Volume: 183
Issue: (9)
Page numbers: 2065-2070.
DOI: 10.1002/macp.1982.021830904

Abstract: The template effect of polymers containing the adenine residue, 6, bound to a polystyrene backbone via a spacer group, on the polycondensation of active esters of thymine, 1, and theophylline, 2, with piperazine was studied in pyridine/methylene chloride or DMF. Template polymers accelerated the polycondensation of 1 with diamines by a factor of 5-20, but the polycondensation of 2 with piperazine showed no considerable template effect.


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