Authors: Haginaka J
, Sanbe H
Uniformly sized molecularly imprinted polymers: their applications to chiral separation and bioanalysis.
Publication date: 2004
Journal: Chinese Journal of Chromatography
Alternative URL: http://www.chrom-china.com/EN/article/downloadArticleFile.do?attachType=PDF&id=9564
Abstract: In this article, the preparation of uniformly sized molecularly imprinted polymers (MIPs) by a multi-step swelling and polymerization method and the use of these for chiral separation and bioanalysis is reported. A restricted access media (RAM)-MIP, a uniformly sized MIP selectively modified with a hydrophilic external layer, for a pseudo-template compound was also prepared. This was done through a combination of molecular imprinting and hydrophilic surface modification techniques and the obtained RAM-MIP was used for direct injection analysis of drugs in biological fluids by a column-switching HPLC system. (Analytical Abstracts 2004)
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