Proceedings title: Polymer Preprints, Japan
Volume number: 51
Abstract: Molecular imprinting, first reported by G. Wulff et al. in 1972, is now an established technique for creating small molecule recognition sites in a cross-linked polymer material. In this report, chiral helical (+)-poly(diphenyl-2-pyridylmethyl methacrylate) (poly(D2PyMA)) as a template and a-(alkoxymethyl)acrylic acids as a monomer in molecular imprinting method were used for creating the gel with chiral helical cavity. Although the polymer gel prepared using methacrylic acid did not show any significant chiral recognition abilities, a-(benzyloxymethyl)acrylic acid derivatives as a monomer afforded the gels with chiral resolution power for the racemates, such as trans-stilbene oxide and Tröger's base, and the substituents (X) on the phenyl group of the monomer greatly affected the recognition ability of the gels.