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Editors: van Amerongen A, Barug D, Lauwaars M
Publisher: Waginingen Academic Publishers
City: Waginingen, Netherlands
ISBN: 90-76998-531
Conference information: Rapid Methods: For Biological And Chemical Contaminants In Food And Feed

Abstract: The use of veterinary drugs, such as antibiotics, hormones, anthelmintics and tranquillisers, is an integral part of an intensive agricultural production involving animals. Screening and/or rapid assays are needed to support effective and affordable regulatory monitoring, and to facilitate self-control programs. An adequate application of such assays will contribute to the safety of food of animal origin and to a relief of public concerns on food safety issues. This chapter comprises a review of rapid diagnostic methods available for the determination of residues of veterinary drugs in the animal production chains. It summarises different principles of analysis involving immuno- and receptor technologies in single and multi-endpoint approaches. Besides microbial growth inhibition and different conventional immuno, enzyme and receptor assays, new technologies in food safety analysis, such as biosensors, cellular bioassays, transcriptomics and proteomics, are discussed. The choice of the analyst for a certain technique to check the absence or presence of a certain residue should, however, fit its purpose, and is discussed comprehensively here as well. Finally, it is concluded that rapid assays are available for many situations for many substances and many analytical matrices, but that developments are ongoing and are going swiftly. The ultimate at-line assay, which can perform remotely and non-destructively multiple analyses with instantaneous results, is yet still very far away