Authors: Tóth B
, László K
, Horvai G
Chromatographic behavior of silica-polymer composite molecularly imprinted materials.
Publication date: 2005
Journal: Journal of Chromatography A
Alternative URL: http://www.sciencedirect.com/science/article/B6TG8-4H68T3G-2/2/ecd268b298b83c162a5f717b1f560858
Abstract: Molecularly imprinted polymers (MIP) have recently been prepared inside the pores of silica based HPLC packing materials. Detailed physical and chromatographic characterization of such a silica-MIP composite material is presented. The chromatographic peak shape obtained with the uniformly sized spherical silica-MIP composite is mainly determined by the nonlinear adsorption isotherm. Comparison of the composite with the conventional sieved and grinded bulk MIP is therefore based on the nonlinear isotherm and not on retention factors and plate numbers
Template and target information: phenytoin
Author keywords: imprinted polymer, HPLC, Nonlinear, composite
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