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Reference type: Journal
Authors: Klodzinska E, Moravcova D, Jandera P, Buszewski B
Article Title: Monolithic continuous beds as a new generation of stationary phase for chromatographic and electro-driven separations.
Publication date: 2006
Journal: Journal of Chromatography A
Volume: 1109
Issue: (1)
Page numbers: 51-59.
DOI: 10.1016/j.chroma.2005.12.024
Alternative URL: http://www.sciencedirect.com/science/article/B6TG8-4J2KXVK-3/2/62bd17a257d181e152179bbf89d52a5a

Abstract: Monolithic supports are a new generation of stationary phases which are typically prepared using a simple molding process carried out within the confines of the capillary. They provide high rates of mass transfer at lower pressure drops, enable much faster separations and the nature of the pores allows easy permeability for large molecules. This review summarizes the current achievements and application of organic polymer-based monolithic columns, silica-based monolithic columns and their application in bioaffinity processing, modern biotechnology, determination of microorganisms and chiral separations. Special attention is paid to microfabricated devices with monolithic supports because their fabrication of particles directly in the channel eliminates the need for a frit and also creates a unique homogeneity of packing
Template and target information: Review - monolithic stationary phases
Author keywords: electrochromatography, Polymer-based monolithic beds, Silica-based monolithic beds, Bioaffinity processing, Determination of microorganisms, Microfabricated devices with monolithic supports


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