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Reference type: Journal
Authors: Hishida Y, Okawa K, Ohya Y, Ouchi T, Uragami T, Miyata T
Article Title: Synthesis of molecularly imprinted gels that shrink in response to target DNA.
Publication date: 2005
Journal: Polymer Preprints, Japan
Volume: 54
Issue: (2)
Page numbers: 4745-4746.

Abstract: Sequence specific DNA-responsive gels were prepared by molecular imprinting using single strand DNA as ligands, which are complementary to target DNA. The DNA-imprinted gel shrank more remarkably in the presence of the target DNA than the nonimprinted gel, but the PAAm gel did not change. The DNA-responsive shrinking of the DNA-imprinted gel is attributed to hybridization between target DNA and DNA ligands. Moreover, the presence of only fullmatch target DNA induced shrinking of the DNA-imprinted gel, but that of one base mismatch DNAs did not Therefore, the DNA-imprinted gels have many potential applications as smart materials for constructing DNArecognition systems
Template and target information: DNA

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