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Reference type: Journal
Authors: Ko DY, Lee HJ, Jeong B
Article Title: Surface-Imprinted, Thermosensitive, Core-Shell Nanosphere for Molecular Recognition.
Publication date: 2006
Journal: Macromolecular Rapid Communications
Volume: 27
Issue: (16)
Page numbers: 1367-1372.
DOI: 10.1002/marc.200600259

Abstract: Summary: The D-glucose imprinted core-shell nanosphere with an average size of ≈60 to 80 nm showed a significant preference for the binding of D-glucose than the non-imprinted core-shell nanosphere. Depending on temperature, the binding site in the shell with N-isopropylacrylamide oligomer underwent a significant change in binding affinity. In addition, the D-glucose imprinted core-shell nanosphere showed a two times higher affinity for D-glucose than L-glucose, suggesting chiral recognition of the binding site. The core-shell nanosphere reported here is a good biomimetic model system with a well-defined morphology, high surface area, and variable binding affinity through a change in temperature.D
Template and target information: glucose, D-glucose
Author keywords: core-shell nanosphere, molecular recognition, surface imprint, thermosensitive polymer

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