Authors: Haginaka J
, Takehira H
, Hosoya K
, Tanaka N
Molecularly imprinted uniform-sized polymer-based stationary phase for naproxen.
Publication date: 1997
Journal: Chemistry Letters
Abstract: A molecularly imprinted uniform-sized polymer-based stationary phase for (S)-naproxen has been prepared using 4-vinylpyridine and ethylenedimethacrylate as a host functional monomer and cross-linker, respectively. The imprinted polymer material could separate naproxen enantiomers with separation factor of 1.74. Further, the materials showed high selectivity for naproxen and moderate selectivity for other 2-arylpropionic acid derivatives. On the other hand, the imprinted polymer material showed little selectivity for other acidic, basic and neutral compounds
Template and target information: (S)-naproxen
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