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Publisher: IEEE
ISBN: ISSN: 10846999 ISBN: 0780394755;978-078039475-9
Volume number: 2006
Conference information: Proceedings of the 19th IEEE International conference on Micro Electro Mechanical Systems (MEMS)

Abstract: This paper reports a novel microfluidic chip integrated with arrayed molecular imprinting polymer (MIP) films for surface plasmon resonance (SPR) phase imaging of specific bio-samples. The SPR imaging system uses a surface-sensitive optical technique to detect two-dimensional spatial phase variation caused by bio-molecules absorbed on a sensing surface composed of highly-specific MIP films. The developed system has a high resolution and a high-throughput screening capability and has been successfully applied to the analysis of multiple bio-molecules without the need for additional labeling in long-term measuring. The innovative microfluidic chip is capable of transporting a specific amount of multiple bio-samples inside multiple microchannels using micropumps/microvalves to the sensing regions where arrayed MIP films are locally deposited such that highly-sensitive, highly-specific bio-sensing can be achieved. ® 2006 IEEE
Template and target information: progesterone
Author keywords: MEMS, Microfluidic, MIP, SPR