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Reference type: Journal
Authors: Fukazawa K, Ishihara K
Article Title: Preparation of biomolecules recognizable artificial cell membrane surface by a novel molecular imprinting method.
Publication date: 2006
Journal: Polymer Preprints, Japan
Volume: 55
Issue: (1)
Page numbers: 2081.

Abstract: Molecular imprinting method is technique for construction of binding sites that can recognize a purpose molecule selectively. To improve a molecule recognition effect, it is necessary to remove a purpose molecule from a matrix after polymerization completely, and to suppress nonspecific adsorption to a non-recognition site of a purpose molecule. We have prepared fluorescein isothiocyanate (FITC) -labeled albumin recognizable artificial cell membrane surface with phospholipid polymer as a molecular imprinting polymer that suppressed nonspecific absorption of protein. Fluorescence microscope observation showed that much FITC-albumin adsorbed on the surface compared to rhodamine labeled hemoglobin selectivity
Author keywords: Biointerface, molecular imprinting, molecular recognition, Phospholipid polymer


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