MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Hishiya T, Takeuchi T
Article Title: Protein-imprinted polymers by using metal complexes.
Publication date: 2006
Journal: Polymer Preprints, Japan
Volume: 55
Issue: (2)
Page numbers: 5006-5007.

Abstract: Protein recognition by synthetic materials is of great interest in biotechnology and nanotechnology. Here we report the immobilization of metal complexes on polymer matrices for the preparation of SPR sensors for proteins by molecular imprinting. Vinyl-modified metal complexes were copolymerized in the presence of RNase A as a template protein on the Au-SAM chip by radical polymerization with methylenebisacrylamide. After the template protein was washed out, the binding affinities of the proteins on the polymer surface were studied by SPR. The SPR sensor chip imprinted with RNase A showed higher affinity and selectivity for the template protein. Furthermore, it was possible to regulate the binding affinities of proteins by the removal or exchange of metals in the imprinted polymers. Molecular recognition of proteins by using metalloporphyrin (Zn(TCPP)) as a functional monomer is also discussed
Template and target information: protein, RNase A
Author keywords: metal complex, molecular imprinting, protein, SPR


  mipdatabase.com logo special offer joke shirt  Lab Hunk Periodic shirt  HE-MAN polymer chemistry shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner