MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Zhang QQ, Kusunoki T, Xu Q, Wang HY, Kobayashi T
Article Title: Porous imprinted polymer membranes prepared by phase separation in compressed liquid CO2.
Publication date: 2007
Journal: Analytical and Bioanalytical Chemistry
Volume: 388
Issue: (3)
Page numbers: 665-673.
DOI: 10.1007/s00216-007-1252-9

Abstract: Phase separation of poly(acrylonitrile - co-methacrylic acid) in compressed liquid CO2 resulted in formation of a porous imprinted membrane which preferentially adsorbed uracil (URA). The cross-section of the membrane was observed by SEM, which revealed its porous structure. The mechanical strength of the membrane indicated formation of a rigid matrix with high tensile strength (4.4 N mm-2). The imprinted membranes bound highly selectively to URA (12.8 μmol g-1) but binding to dimethyluracil (DMURA), thymine, and cytosine was less (0.7, 0.8, and 0.9 μmol g-1, respectively). When DMURA was similarly used to prepare an imprinted membrane in liquid CO2 there was less binding of DMURA to the imprinted membrane obtained. The URA-imprinted membranes were evaluated by IR spectroscopy before and after URA extraction. The results indicated that hydrogen bonding was the mechanism of binding of URA to the imprinted membrane. Competitive binding studies were performed with binary mixtures of URA and its analogues. The URA-imprinted membrane enabled good separation of URA from cytosine, DMURA, and thymine, with separation factors of 3.0, 3.8, and 2.5, respectively. It was confirmed that the compressed liquid CO2 contributed to efficient formation of template substrate sites in the URA-imprinted membrane
Template and target information: uracil, URA, dimethyluracil, DMURA
Author keywords: molecularly imprinted membrane, molecular recognition, Compressed CO2, Membrane adsorbent, URA


  Periodic table Banana Split - the chemical formula for banana split shirt  Periodic table Bag bag  Meerkat somebody mention coffee mug

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner