Abstract: An on-line supported liquid membrane-piezoelectric detection system, based on a molecularly imprinted polymer (SLM-QCM-MIP) manifold, has been developed and applied to the quantitative determination of vanillin in food samples. The analyte is extracted from a donor phase into the hydrophobic membrane, and then back extracted into a second aqueous phase used as the acceptor solution. The quantification of vanillin was performed using a quartz crystal microbalance modified with a molecularly imprinted polymer (MIP). The method shows a linear range between 5 and 65 μM, with a relative standard deviation of +/-4.8% (at 5 μM). The method was validated by analysing food samples and comparing the results with an SLM based on spectrophotometric quantification
Template and target information: vanillin
Author keywords: supported liquid membrane, molecularly imprinted polymer, piezoelectric sensor, Vanillin, Food samples