MIPdatabase
Authors: Wang L, Zhang ZJ
Article Title: Molecular imprinted polymer-based chemiluminescence imaging sensor for the detection of trans-resveratrol.
Publication date: 2007
Journal: Analytica Chimica Acta
Volume: 592
Issue: (2)
Page numbers: 115-120.
DOI: 10.1016/j.aca.2007.04.007
Alternative URL: http://www.sciencedirect.com/science/article/B6TF4-4NFH0DT-6/2/8076a5e491d0d05b73f36526f6b74497
Abstract: Sensitive, rapid and inexpensive chemiluminescence (CL) imaging has been developed based on molecular imprinted polymer (MIP) sensing elements. Imprinted uniform microspheres were synthesized by precipitation polymerization. Microtiter plates (96 wells) were coated with polymer microspheres imprinted with trans-resveratrol, which were fixed in place using poly(vinyl alcohol) (PVA) as glue. The amount of polymer-bound trans-resveratrol was quantified using imidazole (IMZ)-catalyzed peroxyoxalate chemiluminescence (PO-CL) reaction. The light produced was then measured with a high-resolution CCD camera. Calibration curve corresponding to analyte concentration ranging from 0.3 to 25 μg mL-1 was obtained with a limit of detection 0.1 μg mL-1. These results showed that the MIP-based CL imaging sensor can become a useful analytical tool for quick simultaneous detection of trans-resveratrol in a large number of real samples
Template and target information: trans-resveratrol
Author keywords: molecular imprinted polymer, precipitation polymerization, microspheres, Chemiluminescence imaging, trans-resveratrol
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