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Reference type: Journal
Authors: Ma JJ, Wang XL, Xu XY
Article Title: Performance of S-Naproxen Molecularly Imprinted Polymers Prepared by Different Functional Monomers.
Publication date: 2007
Journal: Fine Chemicals
Volume: 24
Issue: (2)
Page numbers: 133-135,153.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTotal-JXHG200702007.htm

Abstract: Using S-naproxen as template,molecularly imprinted polymers P1,P2 and P3 were synthesized by different functional monomers,acrylamide(AM),methacrylic acid(MAA) and N-vinylpyrrolidone(NVP) respectively.By means of UV spectroscopy and computational approach,interaction between the template molecule and functional monomer was studied.The binding energy of the pre-polymerization was calculated by use of PM3 method.Binding isotherms reveal that when the concentration of substrate is 0.1 mmol/L,the amounts of S-naproxen bound to P1,P2 and P3 are 0.360,0.305 and 0.150 μmol respectively.The order of binding capacity of the three kinds of molecularly imprinted polymers is P1P2P3.The results show a positive correlation between the binding quantities and binding energy.
Template and target information: S-naproxen
Author keywords: Molecularly imprinted polymers, functional monomers, computational approach, binding capacity

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