Abstract: A molecularly imprinted polymer was prepared by molecular imprinting technique using acrylamide as monomer,Sudan red III as template molecule and a large excess of ethyleneglycoldimethacrylate as the cross-linking agent.The bulk polymer obtained was investigated in equilibrium binding experiments to evaluate the molecular recognition and binding characteristics of the Sudan red III molecularly imprinted polymer.Scatchard analysis showed that two sites were produced in the polymer matrix and their dissociation constants were calculated to be 8.44×10~(-4)mol/L and 8.12×10~(-3)mol/L,respectively.The substrate selectivity of imprinted polymer and non-imprinted polymer was investigated.The results showed that the imprinted polymer exhibited much higher affinity for Sudan red III among the tested compounds.
Template and target information: Sudan red III
Author keywords: molecular imprinting, Sudan III, molecular recognition, substrates selectivity