MIPdatabase
Authors: Liu HJ, Xiang WZ, Xu WJ, Xiong YQ, Lu YB
Article Title: Synthesis of a Molecularly Imprinted Sulfisoxazole Polymer and Its Selective Binding Characteristics.
Publication date: 2005
Journal: Journal of Instrumental Analysis
Volume: 24
Issue: (2)
Page numbers: 41-44.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTotal-TEST20050200A.htm
Abstract: A molecularly imprinted sulfisoxazole (SIZ) polymer was prepared based on silica gel as sacrificial material. In the procedure, methacrylic acid (MAA) or 4-vinylpyridine (4-Vp) was selected as functional monomers, glycol dimethacrylate (EDMA) as crosslinker. Polymer properties, which were influenced by different functional monomers, were investigated with static adsorption experiments and Scatchard analysis. The results showed that the imprinted polymer with 4-vinylpyridine as functional monomers exhibited good affinity for sulfisoxazole. Scatchard analysis indicated that two different types of binding sites were produced in the polymer matrix and their dissociation constants were 2.01 × 10-4 mol/l and 7.30 × 10-3 mol/l, respectively. (Analytical Abstracts 2005)
Template and target information: sulfisoxazole, SIZ
Author keywords: Sulfisoxazole (SIZ), silica gel, Selective, molecular recognition
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