Abstract: Molecularly imprinted polymer(MIP) which has special molecule recognition ability to aspirin was synthesized with aspirin as template and acrylamide as functional monomer.The result of research indicated that this MIP could specially recognize aspirin molecule through hydrogen-bond interaction,and its static distribution coefficient for aspirin was 5.65.When handling aspirin and its analogs like benzene,benzoic acid,phenyl acetate and salicylic acid,the separation factors were all above 1.89,so the selectivity of MIP for aspirin was high.The maximum surface adsorption quantity and equilibrium deseparation coefficient of MIP toward aspirin were 67.7 mg/g and 2.33×10~(-4) mol/L respectively.The selective adsorption of aspirin on MIP could be accomplished in 30 min.
Template and target information: aspirin, acetylsalicylic acid
Author keywords: Aspirin, molecularly imprinted polymer, Molecule recognition