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Reference type: Book Chapter
Authors: Andersson LI, Nicholls IA, Mosbach K
Publication date: 1995
Chapter title: Antibody mimics obtained by noncovalent molecular imprinting.
Chapter number: 6
Page numbers: 89-96.
DOI: 10.1021/bk-1995-0586.ch006

Book title: Immunoassays of Agrochemicals
Editors: Karu AE, Nelson JO, Wong RB
Publisher: The American Chemical Society
City: Washington DC
ISBN: 0-8412-3149-4
Series title: ACS Symposium Series
Volume number: 586

Abstract: Molecular imprinting is becoming increasingly recognized as a technique for the ready preparation of polymeric materials containing recognition sites of predetermined specificity. In many instances molecularly imprinted polymers show binding affinities approaching those demonstrated by antigen-antibody systems. The imprints are highly specific, with selectivity profiles comparable to those of antibodies often being observed. Imprinted polymers, with their extremely easy preparation from simple chemical components and ligand-selective recognition, may be regarded as effective and efficient mimics of biological antibodies. The use of polymer based antibody mimics in immunoassay-like techniques is discussed


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