MIPs logo MIPdatabase      MIP2018 Conference website
Custom Search
Reference type: Journal
Authors: Guo YS, Zhang Y, Xie JW
Article Title: Liquid chromatographic behavior of molecularly imprinted polymers with anticholinergic drugs as template.
Publication date: 2007
Journal: Pharmaceutical Care and Research
Volume: 7
Issue: (4)
Page numbers: 249-252.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTotal-YXFY200704005.htm

Abstract: Objectives: To synthesize molecularly imprinted polymers (MIP) with three anticholinergic drugs as template and investigate the liquid chromatographic behavior and recognition mechanism of them in different mobile phase systems. Methods: MIP were synthesized in acetonitrile using neotropine hydrochloride, penequinine hydrochloride and bencynonatine hydrochloride as templates, methacrylic acid as functional monomer and trimethylolpropane trimethylacrylate as crosslinker. After that, MIP were crushed, sieved and packed into standard HPLC column. Chromatographic behavior of the three MIP columns were studied in acetic acid-acetonitrile and ammonium acetate-acetonitrile mobile phase systems, respectively. Results: In the former mobile phase system, MIP-LC columns showed strong adsorption to analytes, while in aqueous mobile phase, in contrast to the behavior of C18 column, the retention time of analytes on three MIP-LC columns was tbencynonatinehydrochloride < tneotropinehydrochloride Template and target information: anticholinergic drugs, neotropine hydrochloride, penequinine hydrochloride, bencynonatine hydrochloride
Author keywords: Cholinergic antagonists, Chromatography,High Pressure Liquid, molecularly imprinted polymer


  mipdatabase.com logo special offer joke shirt  Lab Hunk Periodic shirt  HE-MAN polymer chemistry shirt

Molecules Special Issue call     Sensors Special Issue call






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon