Alternatively for mipdatabase quick searches go here

Custom Search

Abstract: Molecularly imprinted polymers have been utilized for specific molecular recognition in HPLC and many useful stationary phases have been developed. Although these stationary phases show quite high separation factors between the template molecule and its enantiomer or isomers, the reported column efficiencies are not very high. This is because the imprinted polymers were prepared using a bulk polymerization technique and the resultant polymer block must be ground and sieved to be used is a HPLC packing material. We have developed uniformly sized, molecularly imprinted polymer particles to avoid these time-consuming procedures and to achieve higher column efficiencies. A two-step swelling and polymerization technique affords uniformly sized. polymer particles. When an appropriate template is involved in the system, molecularly imprinted polymer particles with excellent size uniformity can be obtained. These stationary phases show comparable separation factors with much high column efficiency so the resolution is much better in comparison with stationary phases prepared by bulk polymerization technique