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Reference type: Journal
Authors: Haginaka J
Article Title: Monodispersed, molecularly imprinted polymers as affinity-based chromatography media.
Publication date: 2008
Journal: Journal of Chromatography B
Volume: 866
Issue: (1-2)
Page numbers: 3-13.
DOI: 10.1016/j.jchromb.2007.07.019
Alternative URL: http://www.sciencedirect.com/science/article/B6X0P-4P6VDJ0-1/1/07a4c61a4268e7d8e72399853743eb60

Abstract: This review article deals with preparation methods for spherical and monodispersed molecularly imprinted polymers (MIPs) in micrometer sizes. Those methods include suspension polymerization in water, liquid perfluorocarbon and mineral oil, seed polymerization and dispersion/precipitation polymerization. The other methods are the use of beaded materials such as a spherical silica or organic polymer for grafting MIP phases onto the surfaces of porous materials or filling the pores of silica with MIPs followed by dissolution of the silica. Furthermore, applications of MIP microspheres as affinity-based chromatography media, HPLC stationary phases and solid-phase extraction media, will be discussed for pharmaceutical, biomedical and environmental analysis
Author keywords: molecularly imprinted polymer, Monodispersed MIP, MIP microsphere, Affinity-based media, pharmaceutical analysis, environmental analysis, bioanalysis

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