MIPdatabase
Authors: Kozulic B, Heimgartner U
Publication date: 1996
Chapter title: Hydrophilic and Amphiphatic Monomers and use of their Gels as Separation Media.
Chapter number: 27
Page numbers: 593-604.
DOI: 10.1016/S1569-2558(08)60139-3 Alternative URL: http://www.sciencedirect.com/science/article/B7CTF-4SMFKMJ-Y/1/a2f40923da5deaf6a8659804849d8210
Book title: Biochemical Technology
Editors: Bittar EE, Danielsson B, Bulow L
Publisher: Elsevier
City: Amsterdam
Series title: Advances in Molecular and Cell Biology
Volume number: 15B
Abstract: In this contribution we describe some results of the work carried out by Professor Klaus Mosbach's group at the Swiss Federal Institute of Technology and later at Elchrom. Synthesis of new acrylic monomers was required for the protein imprinting project and, after the finding that N-acryloyl-tris(hydroxymethyl)aminomethane gels offer advantages for electrophoresis, several series of monomers were synthesized and used to prepare separation media. Particularly useful were hydrophilic monomers based on amino sugar alcohols and corresponding amphiphatic monomers that enable separation of proteins by hydrophobic interaction electrophoresis
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