MIPdatabase
Authors: Sadowska M, Wandelt B
Article Title: Molecularly Imprinted Thin Polymeric Film as a Fluorescent Sensor for Nucleotides.
Publication date: 2008
Journal: Molecular Crystals And Liquid Crystals
Volume: 486
Issue: (1)
Page numbers: 203-212.
DOI: 10.1080/15421400801918005
Abstract: The technology of molecular imprinting of polymers (MIPs) was used to obtain optical sensors for nucleotides. The methacrylates were used as functional monomers and 1,3-diphenyl-6-vinyl-1H-pyrazole-[3,4-b]-quinoline (PAQ) was used as a fluorescent receptor and the nucleotides: guanosine 3GǦ,5GǦ-cyclic monophosphate (cGMP) and adenosine 3GǦ,5GǦ-cyclic monophosphate (cAMP) were a template. The optical sensor obtained as a thin-layer polymeric films was investigated by steady-state fluorescence spectroscopy. The calculated association constant of the cGMP imprinted sensor is Ka-á=-á1.7-á+ù-á104-áM-1 and of cAMP imprinted sensor Ka-á=-á9.9-á+ù-á104-áM-1
Template and target information: guanosine 3',5'-cyclic monophosphate, cGMP, adenosine 3',5'-cyclic monophosphate, cAMP
Author keywords: fluorescence spectroscopy, MIPs, nucleotides, optical sensors, pyrazolequinolines
Join the Society for Molecular Imprinting
New items RSS feed
View latest updatesSign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.
Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
