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Authors: Lachová M, Lehotay J, Skacáni I, Cizmárik J
Article Title: Isolation of Some Derivatives of Phenylcarbamic Acid from Human Plasma using Molecularly Imprinted Polymers.
Publication date: 2009
Journal: Journal of Liquid Chromatography & Related Technologies
Volume: 32
Issue: (2)
Page numbers: 167-181.
DOI: 10.1080/10826070802602890
Alternative URL: http://www.informaworld.com/10.1080/10826070802602890
Abstract: Two molecularly imprinted polymers for 1-methyl-2-piperidinoethyl ester of 4-decyloxyphenylcarbamic acid (template) have been synthesized using a non-covalent imprinting approach. Acrylamid and methacrylic acid, respectively, were used as the functional monomers. Imprinted polymers were used as the sorbents for solid phase extraction (MISPE). The capacity and selectivity of prepared imprinted polymers was investigated. The non-imprinted (blank) polymers were prepared by the same way, without the template, to study the non-specific interactions. Molecularly imprinted polymers were used to extract derivatives of alkoxyphenylcarbamic acid from spiked human plasma. C18 sorbent was also used for SPE to compare the efficiency of the procedure.
Template and target information: 1-methyl-2-piperidinoethyl ester of 4-decyloxyphenylcarbamic acid
Author keywords: HPLC, molecularly imprinted polymer, SPE
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