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Abstract: Molecular imprinted technique has the characteristics of specificity and high selectivity. Its key is the screening of functional monomer and template molecule, polymerization and the elution of template molecule. The preparation methods of molecular imprinted polymers include embedding method, affinity imprinting method, freeze-drying method and surface imprinted method. Molecular imprinting technique is widely applied to analytical chemistry such as chromatographic analysis, environmental trace analysis, membrane separation, chiral separation, and the separation/enrichment of metal ions, sample pretreatment, sensor and the screening of effective components in Chinese drugs. The research direction for molecular imprinted technique in future includes understanding the mechanism of molecular imprinting and identification from molecular level, exploring new synthetic method, realizing the transfer of molecular imprinting technique from organic phase to water phase, from non-polar solvent environment to polar solvent environment and extending its application field
Template and target information: Review - MIPs in analytical chemistry
Author keywords: chiral separation, chromatographic separation, molecular imprinted polymer, Molecular imprinted technique, solid phase extraction