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Abstract: A voltammetric sensor for sensitive and specific determination of trans-resveratrol (RES) were prepared based on immobilization of an RES-imprinted film on the surface of functionalized Indium Tin Oxide (ITO) electrode, which was modified with gamma-methacyloxypropyl trimethoxysilane (gamma-MPS). Cyclic Voltammetry (CV) was presented to extract RES from the molecularly imprinted polymer film and RES were extracted rapidly and completely. The binding performance of the imprinted electrode with the template RES were investigated using differential pulse voltammetry (DPV). The results showed that the imprinted ITO film can give selective recognition to the template RES over that of structurally analogous molecules. A linear response to RES in the concentration range of 2.0×10-6 M to 2.0×10-5 M was observed with a correlation coefficient of 0.992, and the detection limit of the electrochemical sensor was 8.0×10-7 M. Whereas, binding to the reference nonimprinted electrode, made in the same way but without the addition of template RES, there was almost no response to RES
Template and target information: trans-resveratrol, RES, resveratrol
Author keywords: Molecularly imprinted polymers, Electrochemical sensor, resveratrol, Indium tin oxide electrode