Abstract: Molecularly imprinted polymer - copolymer of methacrylic acid (MAA) and ethyleneglycol dimethacrylate (EGDMA) with imprints of metoprolol molecules was synthesized. To optimize conditions of its synthesis, the following parameters were studied: influence of molar ratio of the monomer (MAA) to the crosslinker (EGDMA), chemical nature of porogen, and its volume ratio to monomers mixture on the porous structure of the final copolymer.
In order to study the sorption properties of this polymeric material, the recoveries and breakthrough volume of metoprolol and vitamin B6 were determined. Their values are compared with those obtained for the MAA-EGDMA reference copolymer
Template and target information: metoprolol, vitamin B6
Author keywords: Ethyleneglycol dimethacrylate, methacrylic acid, Metoprolol, molecular imprinting