Authors: Kugimiya A
, Matsui J
, Takeuchi T
, Yano K
, Muguruma H
, Elgersma AV
, Karube I
Recognition of sialic-acid using molecularly imprinted polymer.
Publication date: 1995
Journal: Analytical Letters
Alternative URL: http://www.informaworld.com/10.1080/00032719508000375
Abstract: The molecular imprinting technique was applied for the preparation of a polymer selective for sialic acid. To evaluate its binding ability the molecularly imprinted polymer obtained was used as a stationary phase in liquid chromatography. The polymer showed pH-dependent characteristics for binding: an optimum specificity to sialic acid at pH 8.1 and a higher affinity with group selectivity for cis-diol containing sugars at higher pH
Template and target information: sialic acid
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