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Reference type: Journal
Authors: Kugimiya A, Kuwada Y, Takeuchi T
Article Title: Preparation of sterol-imprinted polymers with the use of 2-(methacryloyloxy)ethyl phosphate.
Publication date: 2001
Journal: Journal of Chromatography A
Volume: 938
Issue: (1-2)
Page numbers: 131-135.
DOI: 10.1016/S0021-9673(01)01384-X

Abstract: Steroid-selective polymers were prepared by the molecular imprinting technique, using 2-(methacryloyloxy)ethyl phosphate as functional monomer. The retentivity and selectivity of the obtained imprinted polymers were evaluated by liquid chromatography. The cholesterol-imprinted polymer showed higher affinity for cholesterol than that for cholesterol derivatives. The selectivity of the imprinted polymer was superior to the imprinted polymer prepared with the conventional functional monomer, 2-(trifluoromethyl)acrylic acid. Estradiol was also imprinted and gave similar results, demonstrating that 2- (methacryloyloxy)ethyl phosphate would be suitable for imprinted polymers of cholesterol and related compounds. (C) 2001 Elsevier Science B.V. All rights reserved
Template and target information: cholesterol, estradiol

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