MIPs logo MIPdatabase      MIP2024 Conference banner, website is now open, register on site for important updates   
Custom Search
Reference type: Journal
Authors: Zhang ZH, Liu L, Nie LH
Article Title: Preparation of Erythromycin-Imprinted Solid-Phase Extraction Material by Sol-Gel Method and the Selective Adsorption.
Publication date: 2010
Journal: Acta Polymerica Sinica
Issue: (6)
Page numbers: 677-683.
Alternative URL: http://www.gfzxb.org/EN/abstract/abstract8871.shtml

Abstract: A highly selective molecularly imprinted polymer (MIP) was prepared by a simple molecular imprinting technique with a sol-gel process. Erythromycin was used as template, 3-aminopropyltrimethoxysilane (APTMS) as functional monomer and tetraethylorthosilicate (TEOS) as reticulating agent. Infrared spectroscopy, scanning electron microscopy, thermogravimetric and surface area analyses were used to characterize the composite structure and morphology in detail. The results showed that the specific surface area of MIP was 266. 2 m(2)/g. These imprinted polymer particles had perfect spherical shape with average size of 600 nm and exhibited especially selective recognition for erythromycin. Equilibrium binding experiment showed that the separation factor was 2.20 when erythromycin was separated by using MIP. The elution condition was optimized, and the optimal condition was methane: acetic acid (75:25, V/V) as eluent, and the optimal elution volume was 15 mL. The recovery of erythromycin was 103.1% by using 15 mL mixture of methane: acetic acid (75:25, V/V) as eluent. Packed in solid phase extraction column, the polymer was used to extract erythromycin from erythromycin enteric-coated tablets. The results indicated that the polymer can separation and enrich erythromycin from erythromycin enteric-coated tablets successfully with the recovery of 104.5%
Template and target information: erythromycin
Author keywords: sol-gel, solid phase extraction, Erythromycin, molecularly imprinted


  MIPs are Forever spoof movie poster shirt  Chemistry peptide mug  Chemists are fun customisable shirt






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner