Authors: Wang Y
, Chai ZH
, He HY
, Jiang YZ
, Fu GQ
Polyacrylamide hydrogels with phenylboronic acid moieties for the imprinting of proteins.
Publication date: 2010
Journal: Chinese Chemical Letters
Alternative URL: http://www.sciencedirect.com/science/article/B8G3X-514YTHX-6/2/75dab4bc221dfa66a5701ae3cdec0c79
Abstract: In this letter, N-acryloyl-3-aminophenylboronic acid (AAPBA) was synthesized and then examined as a new functional monomer for protein imprinting. It was allowed to be copolymerized with acrylamide to produce hemoglobin- or lysozyme-imprinted hydrogels. In template rebinding tests, the imprinted gels showed significant increase in the specific binding with the increase of the AAPBA amounts in the prepolymerization recipes. These results indicate that AAPBA may be a useful functional monomer for its moderate interactions with protein molecules
Template and target information: protein, hemoglobin, lysozyme
Author keywords: protein imprinting, hydrogels, hemoglobin, lysozyme, 3-aminophenylboronic acid
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