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Abstract: A template molecule of D-naproxen was selected as the target. A differential ultraviolet absorption spectrum analysis method was designed to verify the nature of molecular interaction between naproxen and functional monomer. The facts proved that supra-molecular complex is formed by self-assembly through the non-covalent, including: hydrogen bonding and ionic bond. A group of molecular imprinted polymers (MIP), synthesized in different amount of solvent, were analyzed by infrared spectra. It shows that these products have the necessary characteristics of the structure. The transmission electron microscopy was firstly used to observe the morphology of MIP, by which the pore-forming mechanism and the effect of the solvent were investigated. And those MIP were also tested in the adsorption kinetics experiments to testify the influence of morphology factors on the materials' adsorption properties. According to the calculation results of the selectivity assay for the synthetic MIP, the specific absorption capacity index and the imprint factor were obtained. It was up to 3.756
Template and target information: naproxen, D-naproxen
Author keywords: D-naproxen, molecular imprinting, molecular recognition materials, Supra-molecular complex