Alternatively for mipdatabase quick searches go here

Custom Search

Abstract: To assess the potential risks associated with the environmental exposure of steroid estrogens, a novel highly efficient and selective estrogen enrichment procedure based on the use of molecularly imprinted polymer has been developed and evaluated. Herein, analogue of estrogens, namely 17-ethyl estradiol (EE2) was used as the pseudo template, to avoid the leakage of a trace amount of the target analytes. The resulting pseudo molecularly imprinted polymers (PMIPs) showed large sorption capacity, high recognition ability and fast binding kinetics for estrogens. Moreover, using these imprinted particles as dispersive solid-phase extraction (DSPE) materials, the amounts of three estrogens (E1, E2 and E3) which were detected by HPLC-UV from the chicken tissue samples were 0.28, 0.31 and 0.17 μg g-1, and the recoveries were 72.5-78.7%, 90.3-95.2% and 80.5-83.6% in spiked chicken tissue samples with RSD <7%, respectively. All these results reveal that EE2-PMIPs as DSPE materials coupled with HPLC-UV could be applied to the highly selective separation and sensitive determination of trace estrogens in chicken tissue samples
Template and target information: 17-ethyl estradiol, EE2, pseudo template, estrone, E1, 17β-estradiol, E2, estriol, E3, estrogens
Author keywords: Molecularly imprinted polymers, Pseudo template, Estrogen, Dispersive solid-phase extraction, chicken tissue