MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Zhou WH, Guo XC, Zhao HQ, Wu SX, Yang HH, Wang XR
Article Title: Molecularly imprinted polymer for selective extraction of domoic acid from seafood coupled with high-performance liquid chromatographic determination.
Publication date: 2011
Journal: Talanta
Volume: 84
Issue: (3)
Page numbers: 777-782.
DOI: 10.1016/j.talanta.2011.02.004
Alternative URL: http://www.sciencedirect.com/science/article/B6THP-5282JPY-1/2/c1c767f7403e96c5325352f1422a90d9

Abstract: In this work, a highly selective sample cleanup procedure that combining molecular imprinting technique (MIT) and solid phase extraction (SPE) was developed for the isolation of domoic acid (a fascinating marine toxin) from seafood samples. The molecular imprinting polymer (MIP) for domoic acid was prepared using 1,3,5-pentanetricarboxylic acid as the template molecule instead of domoic acid. 4-Vinyl pyridine was used as the functional monomer and ethylene glycol dimethacrylate was used as the cross-linking monomer. The obtained imprinted polymer showed high affinity to domoic acid and was used as selective sorbent for the SPE of domoic acid from seafood samples. An off-line molecularly imprinted solid phase extraction (MISPE) method followed by high-performance liquid chromatography (HPLC) with diode-array detection for the detection of domoic acid was also established. Good linearity was obtained from 0.5 mg L-1 to 25 mg L-1 (R2 > 0.99) with a quantitation limit of 0.1 mg L-1, which was sufficient to determine domoic acid at the maximum level permitted by several authorities. The mean recoveries of domoic acid from mussel extracts were 93.4-96.7%. It was demonstrated that the proposed MISPE-HPLC method could be applied to direct determination of domoic acid from seafood samples
Template and target information: 1,3,5-pentanetricarboxylic acid, domoic acid
Author keywords: Molecular imprinting polymer (MIP), solid phase extraction (SPE), Domoic acid, Marine toxin, Amnesic shellfish poisoning (ASP), Seafood


  mipdatabase.com logo special offer joke shirt  Lab Chick Periodic table shirt  HE-MAN polymer chemistry shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner