Abstract: By utilizing bovine hemoglobin as template,AIBN as photo initiator, TEGDMA-MMA (TEGDMA as crosslinker and MMA as functional monomer) and TEGDMA molecularly imprinted polymer(MIP) menbranes were synthesized on the quartz crystal microbalance under the condition of UV-irradiation, respectively, response signal of different membranes to template protein was characterized by quartz crystal microbalance(QCM),and the capacity of two different MIP material membrane surfaces on the adsorption of bovine hemoglobin were compared. The results showed that MIP-based QCM biosensor exhibited excellent selective capacity in adsorbing bovine hemoglobin.
Template and target information: protein, bovine hemoglobin
Author keywords: quartz crystal microbalance, Molecularly imprinted polymer membrane, biosensor, adsorption capacity