Abstract: In this study,molecularly imprinted polymer(MIP) nano-films for theophylline were prepared on the surface of silica microspheres through reversible addition-fragmentation chain transfer(RAFT) polymerization.The theophylline binding analysis showed that,compared with the control polymer nano-films hybridizing silica microspheres,the MIP nano-films hybridizing silica microspheres had higher affinity for theophylline.Utilizing the controllable nature of RAFT,we could control the growth of MIP nano-films on the silica microspheres.Thus it is possible to tailor the resulting microspheres to have high capacities by growing thicker MIP nano-films or higher binding efficiency by growing thinner MIP nano-films.
Template and target information: theophylline
Author keywords: Molecularly imprinted polymers, controlled, living radical polymerization, nano-films