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Reference type: Journal
Authors: Li M, Zhang JK, Zhang ZY, Zhang BB, Fan T, Wu P
Article Title: Rapid detection of digoxin in serum samples by molecular imprinted biosensor.
Publication date: 2011
Journal: Chinese Journal of Bioprocess Engineering
Volume: 9
Issue: (2)
Page numbers: 64-67.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTotal-SWJG201102016.htm

Abstract: The biosensor was prepared by molecular imprinted technique with digoxin-specific adsorption properties. Firstly the imprinted polymer particles were prepared. Then, particles and the agarose were mixed in proportion. The molecular imprinted polymer film sensor for the digoxin was fixed by the mixture on a glassy carbon electrode (GC). The sensor had specific combination of template molecule-digoxin and its electrochemical signals associated with the template concentration. Thus, it could be used to detect digoxin levels in serum. The molecular imprinted biosensor had advantages of simple, low cost, rapid detection, high specificity, and good stability. The detection limit of the biosensor was 1.28 nmol/L and detection time was 5 min.
Template and target information: digoxin
Author keywords: molecular imprinted sensor, Digoxin, polymer, serum, rapid detection


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