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Reference type: Journal
Authors: Martin PD, Wilson TD, Wilson ID, Jones GR
Article Title: An unexpected selectivity of a propranolol-derived molecular imprint for tamoxifen.
Publication date: 2001
Journal: Analyst
Volume: 126
Issue: (6)
Page numbers: 757-759.
DOI: 10.1039/b102424h

Abstract: During the evaluation of molecular imprinted polymers (MIPs) prepared against the drug tamoxifen a propranolol-derived MIP was used as a positive control. Surprisingly the propranolol- derived MIP showed considerable selectivity towards tamoxifen, and was indeed much more selective than the MIP prepared using tamoxifen as the imprint molecule. The consequences of this unexpected, cross reactivity for the use of MIPs in analytical chemistry is discussed

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