Alternatively for mipdatabase quick searches go here

Custom Search

Abstract: A comprehensive report on molecularly imprinted monolayers (MIMs) is presented, but does not include bulk-polymer thin film coatings on surfaces, inorganic surface imprinting, polymer grafting and layer-by-layer methods. Due to difficulties in imprinting large molecules and obtaining fast binding responses with traditional network polymer materials, MIMs have been developed with the aim of enhancing mass-transfer of analytes in imprinted materials. Three approaches to MIM fabrication have been developed with respect to the formation of the pre-organized template-matrix complex. In the first approach, the molecular binding sites are formed in a monolayer on a glass or gold surface. The second approach uses a template-macromolecule complex to form binding sites in the solution phase that are immobilized onto a surface; and the third approach transfers an imprinted Langmuir film onto a gold surface. Mass transfer in these MIMs in most cases is on the order of minutes, and both small and large molecules (proteins) have been imprinted. Copyright © 2011 John Wiley & Sons, Ltd
Template and target information: Review - MIPs monolayers
Author keywords: molecular imprinting, self-assembled monolayers, surface imprinting, molecular recognition