MIPdatabase
Authors: Ezhova NM, Garkushina IS, Pisarev OA
Article Title: Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin.
Publication date: 2011
Journal: Applied Biochemistry and Microbiology
Volume: 47
Issue: (6)
Page numbers: 635-639.
DOI: 10.1134/S0003683811060056
Abstract: New hydrophilic polymer sorbents comprising reactionary sites which are complementary to a molecule of antibiotic erythromycin were synthesized by the method of molecular imprinting. A series of similar sorbents without reactionary sites was used for comparison of sorption characteristics. Sorption of erythromycin on both types of polymer sorbents synthesized was studied in a wide range of pH and ionic strength. Selectivity of erythromycin sorption on molecularly imprinted cross-linked polymers was shown to depend on the specific interaction of target molecule with polymer matrix. This type of sorbent is perspective for the development of antibiotic purification directly from a culture medium Saccharopolyspora erythreus
Template and target information: erythromycin
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