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Reference type: Journal
Authors: Mangelings D, Vander Heyden Y
Article Title: Enantioselective capillary electrochromatography: Recent developments and new trends.
Publication date: 2011
Journal: Electrophoresis
Volume: 32
Issue: (19)
Page numbers: 2583-2601.
DOI: 10.1002/elps.201100009

Abstract: Since its development in the early 1970s, CEC has been studied quite extensively, but unfortunately its use is still mostly located at an academic level. Reasons for this are the limited availability of commercially available stationary phases (SPs) and columns, along with some practical limitations, such as column fragility, lack of column robustness and reproducibility. Nevertheless, CEC maintains a place among the separation techniques, probably because of its unique feature to combine two separation principles. Also in the field of chiral separations, CEC is often used as a separation technique and already showed its potential for this kind of analyses. This overview will focus on the recent applications, i.e. between 2006 and 2010, in enantioselective analysis by means of CEC. For the selected applications, the used SPs (chiral selectors) and their potential for future method development or screening purposes will be evaluated and critically discussed
Template and target information: Review - enantioselective CEC
Author keywords: capillary electrochromatography, enantioseparations


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