MIPdatabase
Authors: Hou JY, Han XY, Zhang Y, Ding S, Ye L
Publication date: 2011
Article title: Molecularly Imprinted Microspheres for Highly Selective Separation of Diosgenin.
Page numbers: 303-306
DOI: 10.4028/www.scientific.net/AMR.382.303 Alternative URL: http://www.scientific.net/AMR.382.303
Proceedings title: Advanced Materials Research
Editors: Zhang H, Jin D
Publisher: Scientific.net
Volume number: 382
Conference information: Advanced Research on Advanced Structure, Materials and Engineering
Abstract: Molecular imprinting polymers (MIPs) are synthetic materials having specific cavities which are highly specific towards the template molecule. In this paper, diosgenin-imprinted polymer microspheres (DG-MIPs) were prepared by precipitation polymerization, using diosgenin as template, methacrylic acid as functional monomer and ethyleneglycol dimethacrylate as crosslinker. The morphology and adsorption capacity of the microspheres were evaluated by HPLC and Scanning electron microscopy (SEM). The optimal reaction conditions were as follows: 2 mM DG, 6 mM MMA, 60 mM EGDMA and 4 mM AIBN. The method developed might be used to separate and extract effective constituents from Chinese medicinal plants on a large scale.
Template and target information: diosgenin, DG
Author keywords: adsorption capacity, Diosgenin, microspheres, Molecular imprinting polymers (MIPs)
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