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Reference type: Journal
Authors: Tian ML, Li SN, Row KH
Article Title: Molecularly Imprinted Polymer for Solid-Phase Extraction of Ecteinascidin 743 from Sea Squirt.
Publication date: 2012
Journal: Chinese Journal of Chemistry
Volume: 30
Issue: (1)
Page numbers: 43-46.
DOI: 10.1002/cjoc.201180450

Abstract: Ecteinascidin 743 from sea squirt is one of the most original anti-tumoral activity compounds, as proven by the Natural Cancer Institute. Ecteinascidin 743 could be obtained with traditional liquid extraction, but it should be purified and separated from the extract. A molecularly imprinted solid-phase extraction procedure was developed for the selective separation. Ecteinascidin 743 was used as the template and the polymer was synthesized in a methanol environment. Water and n-hexane as the washing solvents can eliminate most of the interference. Good linearity and low relative standard deviations (less than 4.39%) justify its continuing development
Template and target information: Ecteinascidin 743
Author keywords: ecteinascidin 743, molecular imprinted polymer, Solid-phase extraction, sea squirt


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