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Reference type: Conference Proceeding
Authors: Reddy KK, Gobi KV
Publication date: 2011
Article title: Artificial Biomolecular Recognition Element Based Sensor for Electrochemical Impedance Detection of Creatinine.
Page numbers: 25-29
Alternative URL: http://www.ipcbee.com/vol25/6-ICNB2011_Q00018.pdf

Publisher: IACSIT Press
City: Singapore
ISBN: 2010-4618
Volume number: 25
Conference information: Proceedings of the 2011 International Conference on Nanotechnology and Biosensors

Abstract: A novel molecular imprinted polymer (MIP) based electrode has been investigated for electrochemical impedimetric detection of creatinine. Magnitude of impedance was measured in a frequency range of 10 mHz to 60 KHz in the presence and absence of creatinine. Based on the best-fitting equivalence circuit analysis, it was found that the charge-transfer impedance of the electrode increased by the addition of creatinine and increased further with increasing concentrations. Control experiments with non-imprinted polymer (NIP) electrode showed that the sensor is totally non-responsive to creatinine. The low-detectionlimit of the impedance sensor is 50 ng/mL. The sensor surface of the fabricated MIP electrode is easily renewable for repeated cyclic use in multiple analyses.
Template and target information: creatinine
Author keywords: electrochemical impedance, Creatinine sensor, Raman spectroscopy, Molecular Imprinted Material, biosensor, label-free detection


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