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Reference type: Journal
Authors: Okutucu B, Telefoncu A, Haupt K
Article Title: Molecularly Imprinted Polymer for Serotonin Recognition.
Publication date: 2010
Journal: Hacettepe Journal of Biology and Chemistry
Volume: 38
Issue: (2)
Page numbers: 79-84.
Alternative URL: http://www.hjbc.hacettepe.edu.tr/article/38/2/79

Abstract: Developing of new techniques for detecting important biologic molecules are one of the aims of molecular imprinting. Serotonin (5-hydroxytryptamine) is a biogenic amine that acts as a neurotransmitter in the central and peripheral nervous systems. It is present in a variety of organisms, ranging from humans to species such as worms that have primitive nervous systems, and mediates a variety of physiological responses in distinct cell types. Serotonin is one of the indolic compound which has a clinical importance. Serotonin imprinted polymers were synthesized by using different functional monomers. Best results were taken with 2-(trifluoromethyl) acrylic acid and methacrylamide. The binding capacities in different solvents were evaluated. The specifity of polymer was tested by real blood sample.
Template and target information: serotonin, 5-hydroxytryptamine
Author keywords: Serotonin, molecular imprinting, 2-(trifluoromethyl) acrylic acid, molecular recognition, solid phase extraction


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