Alternatively for mipdatabase quick searches go here

Custom Search

Abstract: Beaded Molecule imprinted polymer (MIP) for cinchonan-9-R-ol (cinchonidine) was prepared by suspension polymerization. Particles with the size of 50-70 μm in diameter were collected and evaluated in HPLC mode to separate stereo isomers. Stereo isomers cinchonine and cinchonidine were successfully discriminated with selectivity factor of 2.89 and resolution factor of 0.76. Stereo selectivity of the MIP was found to come from both the interactions between the analyte and carboxyl group on the MIP and the complementary between the stereo structure of imprinted molecule and the MIP. The thermal analysis results showed that the MIP had high thermal stability with initial thermal decomposition temperature of 320 ºC. The pore volume of MIP was 0.1849 mL/g, the specific surface area was 126.84 sqm/g and the average pore diameter was 5.8 nanometer. Scanning electron microscopy showed that MIP had perfect spherical morphology
Template and target information: cinchonan-9-R-ol, cinchonidine