Abstract: The preparation of molecularly imprinted polymer (MIP) microspheres for Erythromycin Ethylsuccinate (EEs) by aqueous suspension polymerization was reported for the first time in this study. The MIPs were prepared by using EEs as template molecule, methacrylic acid (MAA) as functional monomer, ethylene glycol dimethacrylate (EDMA) as cross-linker. The morphological of MIPs was characterized by scanning electron microscopy. The analysis showed that the diameter of MIPs could be controlled about 60 μm. The binding behavior of the template EEs on the MIPs was evaluated by UV-Vis spectrophotometric analysis. The selectivity analysis indicated that MIPs had a good selectively adsorption ability to EEs
Template and target information: Erythromycin Ethylsuccinate, EEs
Author keywords: Erythromycin Ethylsuccinate, microsphere, Molecularly imprinted polymers, suspension polymerization